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Current News Depression & Antidepressants last updated April 2006 search the news articles archives Acceleration of response to antidepressants by repetitive transcranial magnetic stimulation Most studies have tested the efficacy of repetitive transcranial magnetic stimulation (rTMS) in drug-resistant patients with severe depression. A recent study assessed the effective of rTMS as an adjunct to drug therapy. Patients treated with rTMS had a faster reduction in HAM-D score than those treated with an antidepressant alone. At the end of the 5 week study, however, HAM-D scores were similar in all groups..................................... Click for full news article Association between depression and increased risk of sudden cardiac arrest There have been suggestions that major depression may associated with an increased risk of mortality due to coronary heart disease. The results of a very large study of over 400 000 subjects for 14 years has just been published? The risk of out-of-hospital cardiac arrest for patients with depression was nearly 2-fold higher than for non-depressed subjects even after adjusting for confounding factors such as smoking, heavy alcohol consumption, diabetes and hypertension..........................................Click for full news article Independent effect of depression on inflammatory markers as compared to natural killer cell activity Reduced natural killer (NK) cell activity has been reported in depression but the association with increases of inflammatory markers has not been studied. A recent study showed that NK activity was significantly lower in depressed patients but that levels of IL-6 were increased while other inflammatory markers were unchanged. The two effects were not correlated.................................... Click for full news article

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