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High risk of suicide in children of suicide attempters
Some studies on families, twins and adoption have demonstrated that suicide runs in families, however the risk factors for hereditary transmission of suicide behaviour from parents to offspring have not been fully determined.
Investigators compared the offspring of two groups of depressed patients, 81 having previously attempted suicide and 55 non-attempters, with 183 and 116 offspring, respectively. Parents and children were evaluated on the basis of psychopathological findings, history of suicide attempt, impulsive agression and exposure to familial environment stressors. The offspring assessment was blind to parent status.
Offspring of parents who had attempted suicide had a six-fold increased risk of attempting suicide compared with offspring of non-attempters. History of sexual abuse in both parents and children, offspring substance abuse, mood disorder, enhanced impulsive aggression and female gender were factors that significantly increased risk.
These results show that the children of suicide attempters are at a high risk of attempting suicide themselves. The authors of this study suggest that clinicians who treat patients having attempted suicide and had a history of sexual abuse, should see their children since their risk of commiting suicide is far from negligible.
Arch Gen Psychiatry 59: 801-807, 2002

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